What is TB-500 (thymosin beta-4 fragment) in research?

TB-500 refers to research materials related to thymosin beta-4 pathways studied in cell migration and repair models. Supplied for qualified laboratory use only.

Is TB-500 for sale suitable for in vivo studies?

Any in vivo protocol must be designed and approved by your institution. Our material is sold as a research reference with documentation for analytical verification.

What documentation comes with TB-500?

Specification data and COA information are available per batch. Use the COA request form on the product page if you need documentation before purchase.

How is TB-500 quality controlled?

Batches are tied to testing records and purity statements on the COA. Match your vial batch ID to the documentation issued for that lot.

TB-500 research peptide - Science Based Peptides

For laboratory research use only. Not for human consumption.

Research Compounds

TB-500 For Sale

Name: TB-500
Brand: Science Based Peptides
SKU: tb-500
Price: 49.99 USD
Availability: InStock

A synthetic compound designed for structured laboratory research.

Dosage

Quantity

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$49.99

Type

Research Peptide

What is TB-500?

TB-500 research material relates to thymosin beta-4 pathway studies in cell migration and tissue repair models. It is sold for in vitro and qualified laboratory research only.

How it Works

TB-500 is evaluated in models examining actin regulation and cell migration. Studies pair peptide identity confirmation with controlled exposure in approved research systems.

Purity & Testing

99% minimum purity (per specification / COA for the active batch). Each lot is tied to batch documentation so researchers can align material received with COA and specification records before use in regulated workflows. Request a COA from this page if you need documentation prior to purchase.

Storage & Handling

Store lyophilized material per label and COA. Solvent selection and working-solution preparation must follow institutional laboratory SOPs.

Research Overview

A synthetic compound designed for structured laboratory research.

Specifications

Compound	TB-500
Presentation	5mg
purity	High Purity
storage	Refrigerated (2-8C recommended)
Molecular formula	C212H350N56O78S
CAS	77591-33-4
Purity	99%
Catalog reference period	56 days

Sources & References

Peer-reviewed research

Annals of the New York Academy of Sciences

Thymosin beta-4: actin regulation and more

2005 · DOI: 10.1196/annals.1359.005 · PMID: 16399924

Goldstein AL, Hannappel E, Kleinman HK

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Annals of the New York Academy of Sciences

Thymosin beta-4: structure, function, and biological properties supporting current and future clinical applications

2010 · DOI: 10.1111/j.1749-6632.2010.05712.x · PMID: 20955328

Crockford D, Turjman N, Allan C, Angel J

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Nature

Thymosin beta-4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair

2004 · DOI: 10.1038/nature03000 · PMID: 15525989

Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D

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Experimental Eye Research

Thymosin beta-4 promotes corneal wound healing and modulates inflammatory mediators in vivo

2002 · DOI: 10.1006/exer.2001.1153 · PMID: 11846516

Sosne G, Szliter EA, Barrett R, Kernacki KA, Kleinman H, Hazlett LD

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Journal of Investigative Dermatology

Thymosin beta-4 accelerates wound healing

1999 · DOI: 10.1046/j.1523-1747.1999.00608.x · PMID: 10417634

Malinda KM, Sidhu GS, Mani H, et al.

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Expert opinion on biological therapy

Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications

2012 · DOI: 10.1517/14712598.2012.634793 · PMID: 22074294

Goldstein AL, Hannappel E, Sosne G, et al.

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Vitamins and hormones

Thymosin beta 4 interactions

2003 · DOI: 10.1016/s0083-6729(03)01008-2 · PMID: 12852258

Bubb MR

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Signal transduction and targeted therapy

Identification of glutamine as a potential therapeutic target in dry eye disease

2025 · DOI: 10.1038/s41392-024-02119-1 · PMID: 39837870

Chen X, Zhang C, Peng F, et al.

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Stem cell reports

Thymosin beta 4 as an Alzheimer disease intervention target identified using human brain organoids

2025 · DOI: 10.1016/j.stemcr.2025.102601 · PMID: 40816274

Zeng PM, Sun XY, Li Y, et al.

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Frequently Asked Questions

What is TB-500 (thymosin beta-4 fragment) in research?: TB-500 refers to research materials related to thymosin beta-4 pathways studied in cell migration and repair models. Supplied for qualified laboratory use only.
Is TB-500 for sale suitable for in vivo studies?: Any in vivo protocol must be designed and approved by your institution. Our material is sold as a research reference with documentation for analytical verification.
What documentation comes with TB-500?: Specification data and COA information are available per batch. Use the COA request form on the product page if you need documentation before purchase.
How is TB-500 quality controlled?: Batches are tied to testing records and purity statements on the COA. Match your vial batch ID to the documentation issued for that lot.